The tubulin fraternity: Alpha to eta

Research output: Contribution to journalReview articlepeer-review

159 Scopus citations

Abstract

Microtubules perform essential and diverse functions in eukaryotic cells. They are required for spindles during mitosis and meiosis, for axonal transport, for organelle positioning, and for cilia and flagella. γ-tubulin is necessary to initiate the assembly of α-β tubulin heterodimers into microtubule polymers. Recent genetic analyses and database searches have added four new members of the tubulin superfamily, which now includes α-, β-, γ-, δ-, ε-, ζ-, and η-tubulin.

Original languageEnglish
Pages (from-to)49-54
Number of pages6
JournalCurrent Opinion in Cell Biology
Volume13
Issue number1
DOIs
StatePublished - Jan 1 2001

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