TY - JOUR
T1 - The tubulin fraternity
T2 - Alpha to eta
AU - Dutcher, S. K.
N1 - Funding Information:
I thank Gary Stormo for help with the phylogenetic analysis and Naomi Morrissett and Steve Johnson for helpful discussions. I thank Tom Giddings for electron micrographs. Work in progress was supported by a grant from the National Institutes of Health.
PY - 2001
Y1 - 2001
N2 - Microtubules perform essential and diverse functions in eukaryotic cells. They are required for spindles during mitosis and meiosis, for axonal transport, for organelle positioning, and for cilia and flagella. γ-tubulin is necessary to initiate the assembly of α-β tubulin heterodimers into microtubule polymers. Recent genetic analyses and database searches have added four new members of the tubulin superfamily, which now includes α-, β-, γ-, δ-, ε-, ζ-, and η-tubulin.
AB - Microtubules perform essential and diverse functions in eukaryotic cells. They are required for spindles during mitosis and meiosis, for axonal transport, for organelle positioning, and for cilia and flagella. γ-tubulin is necessary to initiate the assembly of α-β tubulin heterodimers into microtubule polymers. Recent genetic analyses and database searches have added four new members of the tubulin superfamily, which now includes α-, β-, γ-, δ-, ε-, ζ-, and η-tubulin.
UR - http://www.scopus.com/inward/record.url?scp=0035141277&partnerID=8YFLogxK
U2 - 10.1016/S0955-0674(00)00173-3
DO - 10.1016/S0955-0674(00)00173-3
M3 - Review article
C2 - 11163133
AN - SCOPUS:0035141277
SN - 0955-0674
VL - 13
SP - 49
EP - 54
JO - Current Opinion in Cell Biology
JF - Current Opinion in Cell Biology
IS - 1
ER -