The trans-Golgi network: A late secretory sorting station

Linton M. Traub, Stuart Kornfeld

Research output: Contribution to journalArticlepeer-review

194 Scopus citations


Proteins synthesized on membrane-bound ribosomes are transported through the Golgi apparatus and, on reaching the trans-Golgi network, are sorted for delivery to various cellular destinations. Sorting involves the assembly of cytosol-oriented coat structures which preferentially package cargo into vesicular transport intermediates. Recent studies have shed new light on both the molecular machinery involved and the complexity of the sorting processes.

Original languageEnglish
Pages (from-to)527-533
Number of pages7
JournalCurrent Opinion in Cell Biology
Issue number4
StatePublished - Aug 1997


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