The TCR Takes Some Immune Responsibility

Ashley A. Viehmann Milam, Paul M. Allen

Research output: Contribution to journalShort surveypeer-review

Abstract

In this issue of Immunity, Van Braeckel-Budimmir et al. (2017) reveal that the pathogenic response of mice to a Plasmodium berghei infection is dominated by a Vβ8.1 T cell response. Mice lacking Vβ8.1 T cells fail to mount a pathogenic response, thus showing that the TCR locus can be an Immune response (Ir) gene. In this issue of Immunity, Van Braeckel-Budimmir et al. (2017) reveal that the pathogenic response of mice to a Plasmodium berghei infection is dominated by a Vβ8.1 T cell response. Mice lacking Vβ8.1 T cells fail to mount a pathogenic response, thus showing that the TCR locus can be an Immune response (Ir) gene.

Original languageEnglish
Pages (from-to)803-804
Number of pages2
JournalImmunity
Volume47
Issue number5
DOIs
StatePublished - Nov 21 2017

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