The taxonomy of brain cancer stem cells: What's in a name?

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

With the increasing recognition that stem cells play vital roles in the formation, maintenance, and potential targeted treatment of brain tumors, there has been an exponential increase in basic laboratory and translational research on these cell types. However, there are several different classes of stem cells germane to brain cancer, each with distinct capabilities and functions. In this perspective, we discuss the types of stem cells relevant to brain tumor pathogenesis, and suggest a nomenclature for future preclinical and clinical investigation.

Original languageEnglish
Pages (from-to)241-247
Number of pages7
JournalOncoscience
Volume1
Issue number3
DOIs
StatePublished - Jan 1 2014

Keywords

  • Astrocytoma
  • Cell-of-origin
  • Ependymoma
  • Glioma
  • Progenitor cell
  • Subventricular zone

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