The single copy gene coding for human α1 (IV) procollagen is located at the terminal end of the long arm of chromosome 13

C. D. Boyd, Karen Weliky, Su Ellen Toth-Fejel, Susan B. Deak, Angela M. Christiano, J. W. Mackenzie, Linda J. Sandell, K. Tryggvason, Ellen Magenis

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Abstract

Using dual-laser sorted chromosomes and spot-blot analysis, we have previously assigned genomic DNA sequences coding for human α1(IV) procollagen to chromosome 13 (Pihlajaniemi et al. 1985). By in situ hybridization to normal chromosomes and chromosomes with 13q deletions, we now report the localization of this gene to the terminal end of the long arm of chromosome 13. In addition, Southern and slot blot hybridization analysis clearly show that these genomic sequences are present only once per haploid genome.

Original languageEnglish
Pages (from-to)121-125
Number of pages5
JournalHuman genetics
Volume74
Issue number2
DOIs
StatePublished - Oct 1 1986

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    Boyd, C. D., Weliky, K., Toth-Fejel, S. E., Deak, S. B., Christiano, A. M., Mackenzie, J. W., Sandell, L. J., Tryggvason, K., & Magenis, E. (1986). The single copy gene coding for human α1 (IV) procollagen is located at the terminal end of the long arm of chromosome 13. Human genetics, 74(2), 121-125. https://doi.org/10.1007/BF00282074