The single copy gene coding for human α1 (IV) procollagen is located at the terminal end of the long arm of chromosome 13

C. D. Boyd; Karen Weliky; Su Ellen Toth-Fejel; Susan B. Deak; Angela M. Christiano; J. W. Mackenzie; Linda J. Sandell; K. Tryggvason; Ellen Magenis

doi:10.1007/BF00282074

The single copy gene coding for human α1 (IV) procollagen is located at the terminal end of the long arm of chromosome 13

C. D. Boyd, Karen Weliky, Su Ellen Toth-Fejel, Susan B. Deak, Angela M. Christiano, J. W. Mackenzie, Linda J. Sandell, K. Tryggvason, Ellen Magenis

Department of Orthopedic Surgery

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30 Scopus citations

Abstract

Using dual-laser sorted chromosomes and spot-blot analysis, we have previously assigned genomic DNA sequences coding for human α1(IV) procollagen to chromosome 13 (Pihlajaniemi et al. 1985). By in situ hybridization to normal chromosomes and chromosomes with 13q deletions, we now report the localization of this gene to the terminal end of the long arm of chromosome 13. In addition, Southern and slot blot hybridization analysis clearly show that these genomic sequences are present only once per haploid genome.

Original language	English
Pages (from-to)	121-125
Number of pages	5
Journal	Human genetics
Volume	74
Issue number	2
DOIs	https://doi.org/10.1007/BF00282074
State	Published - Oct 1986

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title = "The single copy gene coding for human α1 (IV) procollagen is located at the terminal end of the long arm of chromosome 13",

abstract = "Using dual-laser sorted chromosomes and spot-blot analysis, we have previously assigned genomic DNA sequences coding for human α1(IV) procollagen to chromosome 13 (Pihlajaniemi et al. 1985). By in situ hybridization to normal chromosomes and chromosomes with 13q deletions, we now report the localization of this gene to the terminal end of the long arm of chromosome 13. In addition, Southern and slot blot hybridization analysis clearly show that these genomic sequences are present only once per haploid genome.",

author = "Boyd, {C. D.} and Karen Weliky and Toth-Fejel, {Su Ellen} and Deak, {Susan B.} and Christiano, {Angela M.} and Mackenzie, {J. W.} and Sandell, {Linda J.} and K. Tryggvason and Ellen Magenis",

year = "1986",

month = oct,

doi = "10.1007/BF00282074",

language = "English",

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journal = "Human genetics",

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T1 - The single copy gene coding for human α1 (IV) procollagen is located at the terminal end of the long arm of chromosome 13

AU - Boyd, C. D.

AU - Weliky, Karen

AU - Toth-Fejel, Su Ellen

AU - Deak, Susan B.

AU - Christiano, Angela M.

AU - Mackenzie, J. W.

AU - Sandell, Linda J.

AU - Tryggvason, K.

AU - Magenis, Ellen

PY - 1986/10

Y1 - 1986/10

N2 - Using dual-laser sorted chromosomes and spot-blot analysis, we have previously assigned genomic DNA sequences coding for human α1(IV) procollagen to chromosome 13 (Pihlajaniemi et al. 1985). By in situ hybridization to normal chromosomes and chromosomes with 13q deletions, we now report the localization of this gene to the terminal end of the long arm of chromosome 13. In addition, Southern and slot blot hybridization analysis clearly show that these genomic sequences are present only once per haploid genome.

AB - Using dual-laser sorted chromosomes and spot-blot analysis, we have previously assigned genomic DNA sequences coding for human α1(IV) procollagen to chromosome 13 (Pihlajaniemi et al. 1985). By in situ hybridization to normal chromosomes and chromosomes with 13q deletions, we now report the localization of this gene to the terminal end of the long arm of chromosome 13. In addition, Southern and slot blot hybridization analysis clearly show that these genomic sequences are present only once per haploid genome.

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U2 - 10.1007/BF00282074

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VL - 74

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EP - 125

JO - Human genetics

JF - Human genetics

IS - 2

ER -

The single copy gene coding for human α1 (IV) procollagen is located at the terminal end of the long arm of chromosome 13

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