The role of viral respiratory infections in the pathogenesis and exacerbation of asthma

Lance Cohen, Mario Castro

Research output: Contribution to journalReview article

16 Scopus citations

Abstract

Respiratory viral infections are implicated in both the pathogenesis and exacerbation of asthma. Infections with respiratory syncytial virus and parainfluenza virus are the major cause of wheezing-related respiratory infections early in life. Infections in early childhood affect the immune system and modify the risk for subsequent development of allergies and asthma. Later in life, rhinovirus and influenza are implicated frequently in the exacerbation of asthma. The management of respiratory viral infections includes adequate prophylaxis and treatment of acute infections. Insights into the mechanism of viral respiratory tract infections will provide therapeutic targets for treatment and possibly the prevention of virus-induced asthma.

Original languageEnglish
Pages (from-to)3-8
Number of pages6
JournalSeminars in Respiratory Infections
Volume18
Issue number1
DOIs
StatePublished - Mar 1 2003

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