The role of Twist1 in mutant huntingtin–induced transcriptional alterations and neurotoxicity

Keyphrases

• Neurotoxicity 100%
• Post-transcriptional Modification 100%
• Twist1 100%
• Huntington's Disease 80%
• Brain-derived Neurotrophic Factor 60%
• Huntingtin 60%
• Knockdown 40%
• Disease Pathogenesis 40%
• Neuronal Death 40%
• Primary Cortical Neurons 40%
• Regulatory Region 20%
• Disease Progression 20%
• Mouse Model 20%
• RNA-seq Analysis 20%
• Cell Death 20%
• Neurodegenerative Diseases 20%
• Gene Expression Changes 20%
• Embryogenesis 20%
• RNA Interference 20%
• Early Events 20%
• Transcriptional Dysregulation 20%
• Neuronal Function 20%
• Epigenetic Mechanisms 20%
• Immature Neurons 20%
• Protein Fragments 20%
• Altered Expression 20%
• Basic Helix-loop-helix (bHLH) 20%
• Neurotrophic Factor Expression 20%
• DNA Hypermethylation 20%
• Abnormal Expansion 20%
• Polyglutamine Repeat 20%

Neuroscience

• Neurotoxicity 100%
• Huntington's Disease 100%
• Brain-Derived Neurotrophic Factor 75%
• Huntingtin 75%
• Neuronal Death 50%
• Gene Expression 25%
• Cell Death 25%
• Neurodegenerative Disorder 25%
• Regulatory Region 25%
• RNA-Seq 25%
• Polyglutamine 25%
• Epigenetic Mechanism 25%
• DNA Methylation 25%
• Neurotrophic Factor Expression 25%
• Basic Helix Loop Helix Transcription Factor 25%

Biochemistry, Genetics and Molecular Biology

• Huntingtin 100%
• Brain-Derived Neurotrophic Factor 100%
• Regulatory Region 33%
• RNA Interference 33%
• Gene Expression 33%
• Mouse Model 33%
• Mediator 33%
• Cell Death 33%
• Embryogenesis 33%
• Revertant 33%
• RNA Sequencing 33%
• Epigenetic Mechanism 33%
• DNA Methylation 33%
• Basic Helix Loop Helix Transcription Factor 33%
• Neurotrophic Factor Expression 33%