TY - JOUR
T1 - The role of ruminant trans fat as a potential nutraceutical in the prevention of cardiovascular disease
AU - Wang, Ye
AU - Jacome-Sosa, M. Miriam
AU - Proctor, Spencer D.
PY - 2012/5/1
Y1 - 2012/5/1
N2 - Dietary trans fat has received increasing attention over the last few years. It is now appreciated that trans fatty acids (TFA) produced by ruminants (rTFA) via 'a natural biohydrogenation reaction' may have disparate health effects from those produced as a by-product of industrial processing present in partially hydrogenated vegetable oils. In this review, we discuss the most recent findings from human and animal intervention studies in order to evaluate the health implications and potential mechanisms of two major rTFA (t11-vaccenic acid and c9,. t11-conjugated linoleic acid) in their purified form as well as in the format of dairy fat with regard to the development of cardiovascular diseases, with the aim to assess the potential of developing rTFA as novel components for functional foods.
AB - Dietary trans fat has received increasing attention over the last few years. It is now appreciated that trans fatty acids (TFA) produced by ruminants (rTFA) via 'a natural biohydrogenation reaction' may have disparate health effects from those produced as a by-product of industrial processing present in partially hydrogenated vegetable oils. In this review, we discuss the most recent findings from human and animal intervention studies in order to evaluate the health implications and potential mechanisms of two major rTFA (t11-vaccenic acid and c9,. t11-conjugated linoleic acid) in their purified form as well as in the format of dairy fat with regard to the development of cardiovascular diseases, with the aim to assess the potential of developing rTFA as novel components for functional foods.
KW - Cardiovascular disease
KW - Conjugated linoleic acid
KW - Dyslipidemia
KW - Metabolic syndrome
KW - Ruminant trans fat
KW - Vaccenic acid
UR - https://www.scopus.com/pages/publications/84858008442
U2 - 10.1016/j.foodres.2011.08.019
DO - 10.1016/j.foodres.2011.08.019
M3 - Article
AN - SCOPUS:84858008442
SN - 0963-9969
VL - 46
SP - 460
EP - 468
JO - Food Research International
JF - Food Research International
IS - 2
ER -