The role of micronutrients in the diet of HIV-1-infected individuals

Giuseppe Nunnari; Christian Coco; Marilia Rita Pinzone; Piero Pavone; Massimiliano Berretta; Michelino Di Rosa; Matthias Schnell; Giorgio Calabrese; Bruno Cacopardo

doi:10.2741/e556

The role of micronutrients in the diet of HIV-1-infected individuals

Giuseppe Nunnari, Christian Coco, Marilia Rita Pinzone, Piero Pavone, Massimiliano Berretta, Michelino Di Rosa, Matthias Schnell, Giorgio Calabrese, Bruno Cacopardo

Division of Infectious Diseases

Research output: Contribution to journal › Article › peer-review

43 Scopus citations

Abstract

Vitamins, zinc and selenium are important micronutrients that play crucial functions at the cellular and molecular level. Immune response of several different cell types can be modulated by these micronutrients. Deficiency in micronutrients has been extensively reported in HIV-1-infected individuals and further correlated with CD4+ T-cell count, HIV-1 plasma viral load, disease progression and mortality. Supplementation by micronutrients has had controversial effects. Thorough future investigations and trials are certainly needed to strategically plan evidence-based interventions. Here, we review the available data on use of micronutrients during the course of HIV-1 infection.

Original language	English
Pages (from-to)	2442-2456
Number of pages	15
Journal	Frontiers in Bioscience - Elite
Volume	4 E
Issue number	7
DOIs	https://doi.org/10.2741/e556
State	Published - Jan 1 2012

Keywords

Anti-oxidants
Diet
HIV
Review
Selenium
Vitamins
Zinc

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10.2741/e556

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abstract = "Vitamins, zinc and selenium are important micronutrients that play crucial functions at the cellular and molecular level. Immune response of several different cell types can be modulated by these micronutrients. Deficiency in micronutrients has been extensively reported in HIV-1-infected individuals and further correlated with CD4+ T-cell count, HIV-1 plasma viral load, disease progression and mortality. Supplementation by micronutrients has had controversial effects. Thorough future investigations and trials are certainly needed to strategically plan evidence-based interventions. Here, we review the available data on use of micronutrients during the course of HIV-1 infection.",

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AU - Coco, Christian

AU - Pinzone, Marilia Rita

AU - Pavone, Piero

AU - Berretta, Massimiliano

AU - Di Rosa, Michelino

AU - Schnell, Matthias

AU - Calabrese, Giorgio

AU - Cacopardo, Bruno

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AB - Vitamins, zinc and selenium are important micronutrients that play crucial functions at the cellular and molecular level. Immune response of several different cell types can be modulated by these micronutrients. Deficiency in micronutrients has been extensively reported in HIV-1-infected individuals and further correlated with CD4+ T-cell count, HIV-1 plasma viral load, disease progression and mortality. Supplementation by micronutrients has had controversial effects. Thorough future investigations and trials are certainly needed to strategically plan evidence-based interventions. Here, we review the available data on use of micronutrients during the course of HIV-1 infection.

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The role of micronutrients in the diet of HIV-1-infected individuals

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