@article{ce89b3000320486e855847bd1181c982,
title = "The role of mhc polymorphism in anti-microbial resistance",
abstract = "The major histocompatibility complex (mhc)-encoded MHC class I and class II molecules present peptide fragments to T cells at every stage of their life (development, survival, persistence and activation). Thereby, these unusually polymorphic molecules critically influence susceptibility to autoimmune and infectious diseases. Here, we examine the mechanistic relationship between mhc polymorphism and anti-microbial resistance/susceptibility.",
keywords = "Bm, CDR regions, CTL, Complementarity-determining region of the TCR, Cytotoxic T lymphocytes, Dm, Immunity, MHC, Mhc mutation arising in the murine H-2 haplotype, Pathogen resistance, T-cell receptor",
author = "Janko Nikolich-{\v Z}ugich and Fremont, {Daved H.} and Miley, {Michael J.} and Ilhem Messaoudi",
note = "Funding Information: Supported in part by USPHS grants CA 86803 (J.N.-Z.) and the NCRR P51 RR 00163 (Core National Primate Center Support Grant) from the National Institutes of Health. Writing a comprehensive overview of MHC biology and disease association is a very difficult task even without page limitations, and is clearly impossible within the constraint of limited space. Realizing that we have failed the criterion of comprehensiveness, we wish to apologize to numerous colleagues whose primary work was not cited, as we were forced to heavily rely on reviews throughout the article. We wish to thank Dr. K.C. Garcia (Stanford University, Palo Alto, CA) for generously contributing figures to this review, and to the members of the Nikolich lab for stimulating discussions.",
year = "2004",
month = apr,
doi = "10.1016/j.micinf.2004.01.006",
language = "English",
volume = "6",
pages = "501--512",
journal = "Microbes and Infection",
issn = "1286-4579",
number = "5",
}