The role of FDG-PET/CT in cervical cancer: Diagnosis, staging, radiation treatment planning and follow-up

Elesyia D. Haynes-Outlaw, Perry W. Grigsby

Research output: Contribution to journalReview article

3 Scopus citations

Abstract

Routine screening has lead to significant improvement in the incidence and mortality of cervical cancer in industrialized nations. Current International Federation of Gynecologists and Obstetricians staging is based mainly on clinical examination, with anatomic conventional imaging modalities, such as CT and MR imaging, also being routinely used. Metabolic imaging using 18F-fluoro-2-deoxy-D-glucose(FDG)-PET provides highly specific, noninvasive pretreatment staging and prognostic information regarding post-therapy, and can detect asymptomatic, potentially curable locoregional recurrences. FDG-PET/CT can also optimize the use of advanced radiation treatment planning techniques, such as image-guided intensity modulated radiation therapy, for cervical cancer and may be of value in the development of additional novel approaches, such as stereotactic body radiation therapy.

Original languageEnglish
Pages (from-to)435-446
Number of pages12
JournalPET Clinics
Volume5
Issue number4
DOIs
StatePublished - Oct 1 2010

Keywords

  • Cancer staging
  • Cervical cancer
  • PET
  • Radiotherapy treatment planning

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