TY - JOUR
T1 - The role of aminocaproic acid in lacrimal surgery in dyskeratosis congenita
AU - Woog, John J.
AU - Dortzbach, Richard K.
AU - Wexler, Stephen A.
AU - Shahidi, Nasrollah T.
PY - 1985/11/15
Y1 - 1985/11/15
N2 - A 14-year-old boy with bilateral epiphora since birth had absent lacrimal puncta, oral leukoplakia, agenesis of the nails, cutaneous dyschromia, and pancytopenia, findings noted in the rare syndrome of dyskeratosis congenita. Bilateral conjunctivodacryocystorhinostomy was complicated by persistent hemorrhage despite preoperative platelet transfusion. The hemorrhage was controlled by administration of an antifibrinolytic agent, aminocaproic acid. Lacrimal excretory anomalies may be the initial manifestation of a serious systemic disorder, dyskeratosis congenita. Surgical management in this disorder should include appropriate hematologic support.
AB - A 14-year-old boy with bilateral epiphora since birth had absent lacrimal puncta, oral leukoplakia, agenesis of the nails, cutaneous dyschromia, and pancytopenia, findings noted in the rare syndrome of dyskeratosis congenita. Bilateral conjunctivodacryocystorhinostomy was complicated by persistent hemorrhage despite preoperative platelet transfusion. The hemorrhage was controlled by administration of an antifibrinolytic agent, aminocaproic acid. Lacrimal excretory anomalies may be the initial manifestation of a serious systemic disorder, dyskeratosis congenita. Surgical management in this disorder should include appropriate hematologic support.
UR - http://www.scopus.com/inward/record.url?scp=0022406131&partnerID=8YFLogxK
U2 - 10.1016/0002-9394(85)90631-2
DO - 10.1016/0002-9394(85)90631-2
M3 - Article
C2 - 4061556
AN - SCOPUS:0022406131
SN - 0002-9394
VL - 100
SP - 728
EP - 732
JO - American journal of ophthalmology
JF - American journal of ophthalmology
IS - 5
ER -