TY - JOUR
T1 - The relation of blood lead and QRS-T angle in American adults
AU - Jing, Jin
AU - Thapa, Susan
AU - Delhey, Leanna
AU - Abouelenein, Saly
AU - Morad, Wesam
AU - Delongchamp, Robert
AU - Faramawi, Mohammed F.
PY - 2019/9/3
Y1 - 2019/9/3
N2 - The QRS-T angle is a key ECG predictor for ventricular arrhythmia. Lead has a strong relation with cardiovascular diseases; however, no study has been conducted to investigate the association between lead exposure and QRS-T angle. Thus, we explored this association in a population-based representative sample: NHANES III. We used the standard 12-lead ECGs to calculate Spatial QRS-T angles. Blood lead concentration was measured using graphite furnace atomic absorption spectrophotometry method. We conducted multivariate weighted logistic regression to adjust for impaired fasting glucose, hypertension, poverty index, age, race, and smoking status. We found that when the log of blood lead increased by one unit, the odds of an abnormal QRS-T angle increased by 34% among men and 4% among women. We suggest the use of QRS-T angle deviation among those who are exposed to lead to detect individuals at risk for adverse cardiovascular outcomes such as arrhythmias.
AB - The QRS-T angle is a key ECG predictor for ventricular arrhythmia. Lead has a strong relation with cardiovascular diseases; however, no study has been conducted to investigate the association between lead exposure and QRS-T angle. Thus, we explored this association in a population-based representative sample: NHANES III. We used the standard 12-lead ECGs to calculate Spatial QRS-T angles. Blood lead concentration was measured using graphite furnace atomic absorption spectrophotometry method. We conducted multivariate weighted logistic regression to adjust for impaired fasting glucose, hypertension, poverty index, age, race, and smoking status. We found that when the log of blood lead increased by one unit, the odds of an abnormal QRS-T angle increased by 34% among men and 4% among women. We suggest the use of QRS-T angle deviation among those who are exposed to lead to detect individuals at risk for adverse cardiovascular outcomes such as arrhythmias.
KW - cardiovascular diseases
KW - Electrocardiogram
KW - environmental toxicant
KW - lead
UR - http://www.scopus.com/inward/record.url?scp=85063544137&partnerID=8YFLogxK
U2 - 10.1080/19338244.2018.1488674
DO - 10.1080/19338244.2018.1488674
M3 - Article
C2 - 29920162
AN - SCOPUS:85063544137
SN - 1933-8244
VL - 74
SP - 287
EP - 291
JO - Archives of Environmental and Occupational Health
JF - Archives of Environmental and Occupational Health
IS - 5
ER -