The radial transmission line as a broad-band shielded exposure system for microwave irradiation of large numbers of culture flasks

Eduardo G. Moros, William L. Straube, William F. Pickard

Research output: Contribution to journalArticlepeer-review

50 Scopus citations

Abstract

The problem of simultaneously exposing large numbers of culture flasks at nominally equivalent incident power densities and with good thermal control is considered, and the radial transmission line (RTL) is proposed as a solution. The electromagnetic design of this structure is discussed, and an extensively bench-tested realization is described. Referred to 1 W of net forward power, the following specific absorption rate (SAR) data were obtained: at 835.62 MHz, 16.0 ± 2.5 mW/kg (mean ± SD) with range (11-22); at 2450 MHz, 245 ± 50 mW/kg with range (130-323). Radio-frequency interference from an RTL driven at roughly 100 W is so low as to be compatible with a cellular base station only 500 in distant. To avoid potential confounding by temperature differences among as many as 144 T-75 flasks distributed over 9 RTLs (six irradiates and three shams), temperature within all flasks was controlled to 37.0 ± 0.3 °C. Experience with over two years of trouble-free operation suggests that the RTL offers a robust, logistically friendly, and environmentally satisfactory solution to the problem of large-scale in vitro experiments in bioelectromagnetics. Bioelectromagnetics 20:65-80, 1999.

Original languageEnglish
Pages (from-to)65-80
Number of pages16
JournalBioelectromagnetics
Volume20
Issue number2
DOIs
StatePublished - 1999

Keywords

  • In vitro exposure system
  • Large plating area
  • Microwave dosimetry
  • Radio-frequency interference
  • Temperature control

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