TY - JOUR
T1 - The qBED track
T2 - A novel genome browser visualization for point processes
AU - Moudgil, Arnav
AU - Li, Daofeng
AU - Hsu, Silas
AU - Purushotham, Deepak
AU - Wang, Ting
AU - Mitra, Robi D.
N1 - Publisher Copyright:
© 2020 The Author(s) 2020. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: [email protected].
PY - 2021/4/15
Y1 - 2021/4/15
N2 - Summary: Transposon calling cards is a genomic assay for identifying transcription factor binding sites in both bulk and single cell experiments. Here, we describe the qBED format, an open, text-based standard for encoding and analyzing calling card data. In parallel, we introduce the qBED track on the WashU Epigenome Browser, a novel visualization that enables researchers to inspect calling card data in their genomic context. Finally, through examples, we demonstrate that qBED files can be used to visualize non-calling card datasets, such as Combined Annotation-Dependent Depletion scores and GWAS/eQTL hits, and thus may have broad utility to the genomics community.
AB - Summary: Transposon calling cards is a genomic assay for identifying transcription factor binding sites in both bulk and single cell experiments. Here, we describe the qBED format, an open, text-based standard for encoding and analyzing calling card data. In parallel, we introduce the qBED track on the WashU Epigenome Browser, a novel visualization that enables researchers to inspect calling card data in their genomic context. Finally, through examples, we demonstrate that qBED files can be used to visualize non-calling card datasets, such as Combined Annotation-Dependent Depletion scores and GWAS/eQTL hits, and thus may have broad utility to the genomics community.
UR - http://www.scopus.com/inward/record.url?scp=85107089978&partnerID=8YFLogxK
U2 - 10.1093/bioinformatics/btaa771
DO - 10.1093/bioinformatics/btaa771
M3 - Article
C2 - 32941613
AN - SCOPUS:85107089978
SN - 1367-4803
VL - 37
SP - 1168
EP - 1170
JO - Bioinformatics
JF - Bioinformatics
IS - 8
ER -