TY - GEN
T1 - The pressure recovery ratio
T2 - 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
AU - Zhang, Wei
AU - Shmuylovich, Leonid
AU - Kovács, Sándor J.
PY - 2009
Y1 - 2009
N2 - Using a simple harmonic oscillator model (PDF formalism), every early filling E-wave can be uniquely described by a set of parameters, (xo, c, and k). Parameter c in the PDF formalism is a damping or relaxation parameter that measures the energy loss during the filling process. Based on Bernoulli's equation and kinematic modeling, we derived a causal correlation between the relaxation parameter c in the PDF formalism and a feature of the pressure contour during filling - the pressure recovery ratio defined by the left ventricular pressure difference between diastasis and minimum pressure, normalized to the pressure difference between a fiducial pressure and minimum pressure [PRR=(PDiastasis-PMin)/(PFiducial- PMin)]. We analyzed multiple heart beats from one human subject to validate the correlation. Further validation among more patients is warranted. PRR is the invasive causal analogue of the noninvasive E-wave relaxation parameter c. PRR has the potential to be calculated using automated methodology in the catheterization lab in real time.
AB - Using a simple harmonic oscillator model (PDF formalism), every early filling E-wave can be uniquely described by a set of parameters, (xo, c, and k). Parameter c in the PDF formalism is a damping or relaxation parameter that measures the energy loss during the filling process. Based on Bernoulli's equation and kinematic modeling, we derived a causal correlation between the relaxation parameter c in the PDF formalism and a feature of the pressure contour during filling - the pressure recovery ratio defined by the left ventricular pressure difference between diastasis and minimum pressure, normalized to the pressure difference between a fiducial pressure and minimum pressure [PRR=(PDiastasis-PMin)/(PFiducial- PMin)]. We analyzed multiple heart beats from one human subject to validate the correlation. Further validation among more patients is warranted. PRR is the invasive causal analogue of the noninvasive E-wave relaxation parameter c. PRR has the potential to be calculated using automated methodology in the catheterization lab in real time.
UR - http://www.scopus.com/inward/record.url?scp=77950992278&partnerID=8YFLogxK
U2 - 10.1109/IEMBS.2009.5333092
DO - 10.1109/IEMBS.2009.5333092
M3 - Conference contribution
C2 - 19963805
AN - SCOPUS:77950992278
SN - 9781424432967
T3 - Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
SP - 3940
EP - 3943
BT - Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society
PB - IEEE Computer Society
Y2 - 2 September 2009 through 6 September 2009
ER -