The persistence of symptom burden: Symptom experience and quality of life of cancer patients across one year

Teresa L. Deshields, Patricia Potter, Sarah Olsen, Jingxia Liu

Research output: Contribution to journalArticlepeer-review

86 Scopus citations

Abstract

Purpose: The purpose of this longitudinal study was to track the symptom experience in a sample of cancer patients, determine the persistence of cancer symptoms and symptom burden, and examine the relationship between symptoms and QOL over time. Methods: Five hundred forty-two patients provided longitudinal data, completing surveys over a 12-month period. Patients had breast, colorectal, gynecologic, lung, or prostate cancer with stage 1, 2, or 3 disease. Surveys included the Memorial Symptom Assessment Scale and the Functional Assessment of Cancer Therapy-General Scale and were administered every 3 months. Demographic and clinical information and comorbidities were collected from the tumor registry. Results: The number and type of symptoms experienced by patients varied by cancer type, but about 90 % of patients reported one or more symptoms-with prostate cancer patients reporting fewer symptoms and colorectal patients, more symptoms. Prostate patients also had the lowest symptom burden at every time point. Overall, symptom burden decreased over time, as did the Physical subscale for the MSAS. Quality of life was stable over time, except for physical well-being, which improved. Quality of life was negatively correlated with symptom burden at every time point. Conclusions: The differences in symptom experience by cancer type suggest that assessment and management of symptoms must be individually tailored or at least adjusted by cancer type. While symptom burden decreased over time, residual symptom burden was still noteworthy. As quality of life was persistently negatively correlated with symptom burden, the results suggest the need for comprehensive symptom assessment and management.

Original languageEnglish
Pages (from-to)1089-1096
Number of pages8
JournalSupportive Care in Cancer
Volume22
Issue number4
DOIs
StatePublished - Apr 2014

Keywords

  • Oncology
  • Quality of life
  • Symptom persistence
  • Symptoms

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