Hemoglobin degradation in malaria parasites appears to be a vital and massive undertaking during introerythrocytic development. An ordered pathway exists that efficiently cotobolizes hemoglobin to yield amino acids that the parasite uses as a nutrient source, and that co-ordinates the resultant heme into a remarkable crystalline structure called hemozoin. Daniel Goldberg and Andrew Slater explain that the enzymes involved are specific and present prime targets for chemotherapeutic intervention.

Original languageEnglish
Pages (from-to)280-283
Number of pages4
JournalParasitology Today
Issue number8
StatePublished - Aug 1992


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