The paracellular channel: Biology, physiology, and disease

Research output: Book/ReportBook

Abstract

The Paracellular Channel: Biology, Physiology and Disease serves as the first volume to offer a cohesive and unifying picture of the critical functions of paracellular channels (tight junctions) in different tissues. This new class of ion channel utilizes a completely different mechanism to create ion passage pathways across the cell junction. This volume outlines common principles that govern the organization and regulation of these diverse cellular structures, describes the methodology of study, and highlights the pathophysiologic consequence of abnormal structure and functions of the paracellular channels in human diseases. Coverage includes biochemical, biophysical, structural, physiologic analyses of the paracellular channel, and new technologies for recording and characterization.

Original languageEnglish
PublisherElsevier
Number of pages248
ISBN (Electronic)9780128146361
ISBN (Print)9780128146354
DOIs
StatePublished - Jun 9 2018
Externally publishedYes

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