TY - JOUR
T1 - The number of valves requiring surgery does not affect early and late survival in redo valvular surgery
AU - Fukunaga, Naoto
AU - Okada, Yukikatsu
AU - Konishi, Yasunobu
AU - Murashita, Takashi
AU - Koyama, Tadaaki
N1 - Publisher Copyright:
© The Author 2014. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.
PY - 2015/7/1
Y1 - 2015/7/1
N2 - OBJECTIVES: The purpose of this study was to determine whether the number of operated valves affects early and late outcomes in redo valvular surgery. METHODS: We analysed 328 consecutive patients who underwent a total of 431 redo valvular surgeries from January 1990 to December 2010. The mean age was 61.5 ± 13.0 years. The main indication for redo surgery was structural valve deterioration (66.1%). We divided these patients into the redo single valvular surgery group (Group S, n = 175; 231 redo surgeries) and the redo multivalvular surgery group (Group M, n = 153; 201 redo surgeries). The mean follow-up period was 6.4 ± 5.8 years. The follow-up rate for late survival was 98.3%. RESULTS: The hospital mortality rate was 6.5% in Group S and 7.0% in Group M (P = 0.85). Logistic regression analysis revealed that advanced age and New York Heart Association (NYHA) functional class III or IV were statistically significant independent risk factors for hospital mortality. Re-exploration for bleeding was more likely to occur in Group M than in Group S. The 5- and 10-year survival rates were 84.8 ± 3.0 and 70.8 ± 4.6% in Group S and 82.0 ± 3.5 and 70.2 ± 4.9% in Group M, respectively, with no statistical difference. Cox regression analysis revealed that advanced age, a left ventricular ejection fraction rate of <60% and redo surgery beyond the first redo were independent negative predictors of late mortality. NYHA functional class I or II was a statistically significant positive predictor of late survival. CONCLUSIONS: The number of valves requiring redo surgery does not negatively impact early or late survival. Mortality is not different whether one or multiple valves need to be tackled in a redo scenario.
AB - OBJECTIVES: The purpose of this study was to determine whether the number of operated valves affects early and late outcomes in redo valvular surgery. METHODS: We analysed 328 consecutive patients who underwent a total of 431 redo valvular surgeries from January 1990 to December 2010. The mean age was 61.5 ± 13.0 years. The main indication for redo surgery was structural valve deterioration (66.1%). We divided these patients into the redo single valvular surgery group (Group S, n = 175; 231 redo surgeries) and the redo multivalvular surgery group (Group M, n = 153; 201 redo surgeries). The mean follow-up period was 6.4 ± 5.8 years. The follow-up rate for late survival was 98.3%. RESULTS: The hospital mortality rate was 6.5% in Group S and 7.0% in Group M (P = 0.85). Logistic regression analysis revealed that advanced age and New York Heart Association (NYHA) functional class III or IV were statistically significant independent risk factors for hospital mortality. Re-exploration for bleeding was more likely to occur in Group M than in Group S. The 5- and 10-year survival rates were 84.8 ± 3.0 and 70.8 ± 4.6% in Group S and 82.0 ± 3.5 and 70.2 ± 4.9% in Group M, respectively, with no statistical difference. Cox regression analysis revealed that advanced age, a left ventricular ejection fraction rate of <60% and redo surgery beyond the first redo were independent negative predictors of late mortality. NYHA functional class I or II was a statistically significant positive predictor of late survival. CONCLUSIONS: The number of valves requiring redo surgery does not negatively impact early or late survival. Mortality is not different whether one or multiple valves need to be tackled in a redo scenario.
KW - Number of valves
KW - Redo valvular surgery
KW - Survival
UR - https://www.scopus.com/pages/publications/84936879287
U2 - 10.1093/ejcts/ezu403
DO - 10.1093/ejcts/ezu403
M3 - Article
C2 - 25354746
AN - SCOPUS:84936879287
SN - 1010-7940
VL - 48
SP - 123
EP - 128
JO - European Journal of Cardio-thoracic Surgery
JF - European Journal of Cardio-thoracic Surgery
IS - 1
ER -