The new role of calcimimetics as vasculotropic agents

Ziyad Al-Aly

doi:10.1038/ki.2008.563

The new role of calcimimetics as vasculotropic agents

Ziyad Al-Aly

Research output: Contribution to journal › Comment/debate

12 Scopus citations

Abstract

The discovery of the calcium-sensing receptor (CaSR) and the development of calcimimetics have provided new insights into calcium homeostasis and new therapeutic opportunities for parathyroid-related disorders. However, the CaSR is also implicated in various other cellular processes, and the translational applications of calcimimetics may not be exclusively calcium-centric. Koleganova et al. describe a novel role for calcimimetics as vasculotropes, which provides the impetus for further studies to characterize their effects on vascular biology.

Original language	English
Pages (from-to)	9-12
Number of pages	4
Journal	Kidney International
Volume	75
Issue number	1
DOIs	https://doi.org/10.1038/ki.2008.563
State	Published - Jan 2009

Access to Document

10.1038/ki.2008.563

Cite this

@article{d44cb8585a234007aa7e012420ad3a7a,

title = "The new role of calcimimetics as vasculotropic agents",

abstract = "The discovery of the calcium-sensing receptor (CaSR) and the development of calcimimetics have provided new insights into calcium homeostasis and new therapeutic opportunities for parathyroid-related disorders. However, the CaSR is also implicated in various other cellular processes, and the translational applications of calcimimetics may not be exclusively calcium-centric. Koleganova et al. describe a novel role for calcimimetics as vasculotropes, which provides the impetus for further studies to characterize their effects on vascular biology.",

author = "Ziyad Al-Aly",

note = "Funding Information: Dr Al-Aly received funding support from Amgen.",

year = "2009",

month = jan,

doi = "10.1038/ki.2008.563",

language = "English",

volume = "75",

pages = "9--12",

journal = "Kidney International",

issn = "0085-2538",

number = "1",

}

TY - JOUR

T1 - The new role of calcimimetics as vasculotropic agents

AU - Al-Aly, Ziyad

N1 - Funding Information: Dr Al-Aly received funding support from Amgen.

PY - 2009/1

Y1 - 2009/1

N2 - The discovery of the calcium-sensing receptor (CaSR) and the development of calcimimetics have provided new insights into calcium homeostasis and new therapeutic opportunities for parathyroid-related disorders. However, the CaSR is also implicated in various other cellular processes, and the translational applications of calcimimetics may not be exclusively calcium-centric. Koleganova et al. describe a novel role for calcimimetics as vasculotropes, which provides the impetus for further studies to characterize their effects on vascular biology.

AB - The discovery of the calcium-sensing receptor (CaSR) and the development of calcimimetics have provided new insights into calcium homeostasis and new therapeutic opportunities for parathyroid-related disorders. However, the CaSR is also implicated in various other cellular processes, and the translational applications of calcimimetics may not be exclusively calcium-centric. Koleganova et al. describe a novel role for calcimimetics as vasculotropes, which provides the impetus for further studies to characterize their effects on vascular biology.

UR - http://www.scopus.com/inward/record.url?scp=58049199368&partnerID=8YFLogxK

U2 - 10.1038/ki.2008.563

DO - 10.1038/ki.2008.563

M3 - Comment/debate

C2 - 19092812

AN - SCOPUS:58049199368

SN - 0085-2538

VL - 75

SP - 9

EP - 12

JO - Kidney International

JF - Kidney International

IS - 1

ER -

The new role of calcimimetics as vasculotropic agents

Abstract

Access to Document

Other files and links

Fingerprint

Cite this