The neurosteroid allopregnanolone protects retinal neurons by effects on autophagy and GABRs/GABA_A receptors in rat glaucoma models

Medicine & Life Sciences

• 3-methyladenine 7%
• Anterior Chamber 5%
• Apoptosis 6%
• Autophagosomes 13%
• Autophagy 66%
• bafilomycin A1 23%
• Cyclodextrins 7%
• diazonaphthalenedisulfonic acid 9%
• Electrons 4%
• GABA-A Receptors 74%
• Ganglia 5%
• Glaucoma 65%
• Immunoblotting 5%
• In Situ Nick-End Labeling 5%
• Injections 3%
• Intraocular Pressure 10%
• Intravitreal Injections 6%
• Light 7%
• Macroautophagy 7%
• Messenger RNA 3%
• Microspheres 5%
• Microtubule-Associated Proteins 12%
• mitochondrial permeability transition pore 7%
• Nerve Fibers 10%
• Neuroprotection 11%
• Neuroprotective Agents 5%
• Neurosteroids 93%
• Ocular Hypertension 6%
• Optic Nerve 5%
• Polymerase Chain Reaction 3%
• Polystyrenes 6%
• Pregnanolone 100%
• Real-Time Polymerase Chain Reaction 4%
• Retina 9%
• Retinal Ganglion Cells 30%
• Retinal Neurons 93%
• Reverse Transcription 4%
• SAR405 24%
• Sequestosome-1 Protein 9%
• Sirolimus 11%
• Therapeutics 1%
• torin 20%
• Vacuoles 11%