The morphogen Sonic hedgehog inhibits its receptor Patched by a pincer grasp mechanism

Amalie F. Rudolf, Maia Kinnebrew, Christiane Kowatsch, T. Bertie Ansell, Kamel El Omari, Benjamin Bishop, Els Pardon, Rebekka A. Schwab, Tomas Malinauskas, Mingxing Qian, Ramona Duman, Douglas F. Covey, Jan Steyaert, Armin Wagner, Mark S.P. Sansom, Rajat Rohatgi, Christian Siebold

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Medicine & Life Sciences