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The mitochondrial calcium uniporter is a highly selective ion channel
Yuriy Kirichok
, Grigory Krapivinsky
, David E. Clapham
Department of Biochemistry & Molecular Biophysics
Research output
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Contribution to journal
›
Article
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peer-review
1256
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Scopus citations
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Keyphrases
Ca2+
100%
Highly Selective
100%
Mitochondrial Calcium Uniporter
100%
Selective Ion Channel
100%
Mitochondrial Ca2+ Uniporter
75%
Ca2+ Uptake
75%
Mitochondria
50%
Intracellular Ca2+
50%
Cell Death
25%
High Affinity
25%
Spatiotemporal Pattern
25%
Patch Clamp
25%
Ion Channels
25%
Dissociation Constant
25%
Electrochemical Gradient
25%
Energy Production
25%
Mitochondrial Ca2+
25%
Inner Membrane
25%
Cytoplasmic Ca2+
25%
ATP Hydrolysis
25%
Turnover number
25%
Inner Mitochondrial Membrane
25%
Direct Coupling
25%
Uniport
25%
Mitochondrial Ca2+ Uptake
25%
ATP Transport
25%
Cytosol
25%
Novel Channel
25%
Ca2+ Selectivity
25%
Biochemistry, Genetics and Molecular Biology
Uniporter
100%
Ion Channel
100%
Mitochondrion
40%
Enzymatic Hydrolysis
20%
Calcium Signaling
20%
Adenosine Triphosphate
20%
Cell Death
20%
Dissociation Constant
20%
Electrochemical Gradient
20%
Turnover Number
20%
Patch Clamp
20%
Energy Yield
20%
Inner Mitochondrial Membrane
20%
Inner Membrane
20%
Neuroscience
Ion Channel
100%
Mitochondrion
66%
Cell Death
33%
Adenosine Triphosphate
33%
Calcium Signaling
33%
Patch Clamp
33%
Inner Membrane
33%
Mitochondrial Membrane
33%