The Mind of a Mouse

Larry F. Abbott; Davi D. Bock; Edward M. Callaway; Winfried Denk; Catherine Dulac; Adrienne L. Fairhall; Ila Fiete; Kristen M. Harris; Moritz Helmstaedter; Viren Jain; Narayanan Kasthuri; Yann LeCun; Jeff W. Lichtman; Peter B. Littlewood; Liqun Luo; John H.R. Maunsell; R. Clay Reid; Bruce R. Rosen; Gerald M. Rubin; Terrence J. Sejnowski; H. Sebastian Seung; Karel Svoboda; David W. Tank; Doris Tsao; David C. Van Essen

doi:10.1016/j.cell.2020.08.010

The Mind of a Mouse

Larry F. Abbott, Davi D. Bock, Edward M. Callaway, Winfried Denk, Catherine Dulac, Adrienne L. Fairhall, Ila Fiete, Kristen M. Harris, Moritz Helmstaedter, Viren Jain, Narayanan Kasthuri, Yann LeCun, Jeff W. Lichtman, Peter B. Littlewood, Liqun Luo, John H.R. Maunsell, R. Clay Reid, Bruce R. Rosen, Gerald M. Rubin, Terrence J. SejnowskiH. Sebastian Seung, Karel Svoboda, David W. Tank, Doris Tsao, David C. Van Essen

Research output: Contribution to journal › Comment/debate

94 Scopus citations

Abstract

Large scientific projects in genomics and astronomy are influential not because they answer any single question but because they enable investigation of continuously arising new questions from the same data-rich sources. Advances in automated mapping of the brain's synaptic connections (connectomics) suggest that the complicated circuits underlying brain function are ripe for analysis. We discuss benefits of mapping a mouse brain at the level of synapses.

Original language	English
Pages (from-to)	1372-1376
Number of pages	5
Journal	Cell
Volume	182
Issue number	6
DOIs	https://doi.org/10.1016/j.cell.2020.08.010
State	Published - Sep 17 2020

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Abbott, L. F., Bock, D. D., Callaway, E. M., Denk, W., Dulac, C., Fairhall, A. L., Fiete, I., Harris, K. M., Helmstaedter, M., Jain, V., Kasthuri, N., LeCun, Y., Lichtman, J. W., Littlewood, P. B., Luo, L., Maunsell, J. H. R., Reid, R. C., Rosen, B. R., Rubin, G. M., ... Van Essen, D. C. (2020). The Mind of a Mouse. Cell, 182(6), 1372-1376. https://doi.org/10.1016/j.cell.2020.08.010

@article{ef0355346e79487dace52e1996920aa5,

title = "The Mind of a Mouse",

abstract = "Large scientific projects in genomics and astronomy are influential not because they answer any single question but because they enable investigation of continuously arising new questions from the same data-rich sources. Advances in automated mapping of the brain's synaptic connections (connectomics) suggest that the complicated circuits underlying brain function are ripe for analysis. We discuss benefits of mapping a mouse brain at the level of synapses.",

author = "Abbott, {Larry F.} and Bock, {Davi D.} and Callaway, {Edward M.} and Winfried Denk and Catherine Dulac and Fairhall, {Adrienne L.} and Ila Fiete and Harris, {Kristen M.} and Moritz Helmstaedter and Viren Jain and Narayanan Kasthuri and Yann LeCun and Lichtman, {Jeff W.} and Littlewood, {Peter B.} and Liqun Luo and Maunsell, {John H.R.} and Reid, {R. Clay} and Rosen, {Bruce R.} and Rubin, {Gerald M.} and Sejnowski, {Terrence J.} and Seung, {H. Sebastian} and Karel Svoboda and Tank, {David W.} and Doris Tsao and {Van Essen}, {David C.}",

note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",

year = "2020",

month = sep,

day = "17",

doi = "10.1016/j.cell.2020.08.010",

language = "English",

volume = "182",

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journal = "Cell",

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Abbott, LF, Bock, DD, Callaway, EM, Denk, W, Dulac, C, Fairhall, AL, Fiete, I, Harris, KM, Helmstaedter, M, Jain, V, Kasthuri, N, LeCun, Y, Lichtman, JW, Littlewood, PB, Luo, L, Maunsell, JHR, Reid, RC, Rosen, BR, Rubin, GM, Sejnowski, TJ, Seung, HS, Svoboda, K, Tank, DW, Tsao, D & Van Essen, DC 2020, 'The Mind of a Mouse', Cell, vol. 182, no. 6, pp. 1372-1376. https://doi.org/10.1016/j.cell.2020.08.010

TY - JOUR

T1 - The Mind of a Mouse

AU - Abbott, Larry F.

AU - Bock, Davi D.

AU - Callaway, Edward M.

AU - Denk, Winfried

AU - Dulac, Catherine

AU - Fairhall, Adrienne L.

AU - Fiete, Ila

AU - Harris, Kristen M.

AU - Helmstaedter, Moritz

AU - Jain, Viren

AU - Kasthuri, Narayanan

AU - LeCun, Yann

AU - Lichtman, Jeff W.

AU - Littlewood, Peter B.

AU - Luo, Liqun

AU - Maunsell, John H.R.

AU - Reid, R. Clay

AU - Rosen, Bruce R.

AU - Rubin, Gerald M.

AU - Sejnowski, Terrence J.

AU - Seung, H. Sebastian

AU - Svoboda, Karel

AU - Tank, David W.

AU - Tsao, Doris

AU - Van Essen, David C.

PY - 2020/9/17

Y1 - 2020/9/17

N2 - Large scientific projects in genomics and astronomy are influential not because they answer any single question but because they enable investigation of continuously arising new questions from the same data-rich sources. Advances in automated mapping of the brain's synaptic connections (connectomics) suggest that the complicated circuits underlying brain function are ripe for analysis. We discuss benefits of mapping a mouse brain at the level of synapses.

AB - Large scientific projects in genomics and astronomy are influential not because they answer any single question but because they enable investigation of continuously arising new questions from the same data-rich sources. Advances in automated mapping of the brain's synaptic connections (connectomics) suggest that the complicated circuits underlying brain function are ripe for analysis. We discuss benefits of mapping a mouse brain at the level of synapses.

UR - http://www.scopus.com/inward/record.url?scp=85090714775&partnerID=8YFLogxK

U2 - 10.1016/j.cell.2020.08.010

DO - 10.1016/j.cell.2020.08.010

M3 - Comment/debate

C2 - 32946777

AN - SCOPUS:85090714775

SN - 0092-8674

VL - 182

SP - 1372

EP - 1376

JO - Cell

JF - Cell

IS - 6

ER -

The Mind of a Mouse

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