The Mevalonate Synthesis Pathway as a Therapeutic Target in Cancer

Keyphrases

• Alendronate 33%
• Anticancer Agents 33%
• Anticancer Therapy 33%
• Bona Fide 33%
• Carcinoma Cell Lines 33%
• Cell Invasiveness 33%
• Cellular Level 33%
• Cellular Processes 33%
• Culture System 33%
• Dose Effect 33%
• Drug-induced 33%
• Farnesyl 33%
• Farnesyl Pyrophosphate 33%
• Farnesyltransferase Inhibitor 66%
• Geranylgeranyl 33%
• Geranylgeranyl Pyrophosphate 33%
• Geranylgeranyl Transferase 33%
• In Cancer 100%
• Isoprenoids 66%
• Mevalonate 100%
• Mevastatin 33%
• Minimal Impact 33%
• Murine Lung 33%
• Phenotypic Change 33%
• Rho Proteins 33%
• Synthesis Pathway 100%
• Systemic Toxicity 33%
• Therapeutic Target 100%
• Therapeutic Value 33%
• Tumor Cell Adhesion 33%
• Tumor Cell Proliferation 33%

Biochemistry, Genetics and Molecular Biology

• Anticancer 100%
• Cell Adhesion 50%
• Cell Invasion 50%
• Cell Proliferation 50%
• Farnesyl Pyrophosphate 50%
• Farnesyltransferase 100%
• Geranylgeranyl Pyrophosphate 50%
• Mevastatin 50%
• Murine 50%
• Rho Factor 50%
• Transferase 50%