The mannose receptor mediates the cellular immune response in human coccidioidomycosis

Neil M. Ampel; Daniel K. Nelson; Lijin Li; Sara O. Dionne; Douglas F. Lake; Keira A. Simmons; Demosthenes Pappagianis

doi:10.1128/IAI.73.4.2554-2555.2005

The mannose receptor mediates the cellular immune response in human coccidioidomycosis

Neil M. Ampel
, Daniel K. Nelson
, Lijin Li
, Sara O. Dionne
, Douglas F. Lake
, Keira A. Simmons
, Demosthenes Pappagianis

Section of Surgical Oncology

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

Mannose is the predominant monosaccharide in the coccidioidal antigen preparation T27K. Mannan and anti-CD206 antibody significantly decreased the surface expression of mannose receptor (MR) on adherent peripheral blood mononuclear cells and reduced the interleukin-2 (IL-2) release induced by T27K. These data suggest that MR mediates IL-2 release by T27K.

Original language	English
Pages (from-to)	2554-2555
Number of pages	2
Journal	Infection and immunity
Volume	73
Issue number	4
DOIs	https://doi.org/10.1128/IAI.73.4.2554-2555.2005
State	Published - Apr 2005

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10.1128/IAI.73.4.2554-2555.2005

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title = "The mannose receptor mediates the cellular immune response in human coccidioidomycosis",

abstract = "Mannose is the predominant monosaccharide in the coccidioidal antigen preparation T27K. Mannan and anti-CD206 antibody significantly decreased the surface expression of mannose receptor (MR) on adherent peripheral blood mononuclear cells and reduced the interleukin-2 (IL-2) release induced by T27K. These data suggest that MR mediates IL-2 release by T27K.",

author = "Ampel, \{Neil M.\} and Nelson, \{Daniel K.\} and Lijin Li and Dionne, \{Sara O.\} and Lake, \{Douglas F.\} and Simmons, \{Keira A.\} and Demosthenes Pappagianis",

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T1 - The mannose receptor mediates the cellular immune response in human coccidioidomycosis

AU - Ampel, Neil M.

AU - Nelson, Daniel K.

AU - Li, Lijin

AU - Dionne, Sara O.

AU - Lake, Douglas F.

AU - Simmons, Keira A.

AU - Pappagianis, Demosthenes

PY - 2005/4

Y1 - 2005/4

N2 - Mannose is the predominant monosaccharide in the coccidioidal antigen preparation T27K. Mannan and anti-CD206 antibody significantly decreased the surface expression of mannose receptor (MR) on adherent peripheral blood mononuclear cells and reduced the interleukin-2 (IL-2) release induced by T27K. These data suggest that MR mediates IL-2 release by T27K.

AB - Mannose is the predominant monosaccharide in the coccidioidal antigen preparation T27K. Mannan and anti-CD206 antibody significantly decreased the surface expression of mannose receptor (MR) on adherent peripheral blood mononuclear cells and reduced the interleukin-2 (IL-2) release induced by T27K. These data suggest that MR mediates IL-2 release by T27K.

UR - https://www.scopus.com/pages/publications/16244370984

U2 - 10.1128/IAI.73.4.2554-2555.2005

DO - 10.1128/IAI.73.4.2554-2555.2005

M3 - Article

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AN - SCOPUS:16244370984

SN - 0019-9567

VL - 73

SP - 2554

EP - 2555

JO - Infection and immunity

JF - Infection and immunity

IS - 4

ER -

The mannose receptor mediates the cellular immune response in human coccidioidomycosis

Abstract

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