The Management of Severe Sepsis and Septic Shock

Matthew R. Morrell; Scott T. Micek; Marin H. Kollef

doi:10.1016/j.idc.2009.04.002

The Management of Severe Sepsis and Septic Shock

Matthew R. Morrell, Scott T. Micek, Marin H. Kollef

Research output: Contribution to journal › Review article › peer-review

30 Scopus citations

Abstract

The diagnosis and management of severe sepsis and septic shock is a complex and dynamic process. Newer evidence-based interventions are constantly being developed and implemented with the purpose of improving morbidity and mortality. Current investigations are being performed in hospital environments to determine the change in behaviors and clinical impact with the most recent recommendations. The use of standardized treatment protocols in addition to newer diagnostic and treatment modalities in patients who have severe sepsis and septic shock can continue to improve patient-related outcomes and the damaging effect of these diseases on society.

Original language	English
Pages (from-to)	485-501
Number of pages	17
Journal	Infectious disease clinics of North America
Volume	23
Issue number	3
DOIs	https://doi.org/10.1016/j.idc.2009.04.002
State	Published - Sep 2009

Keywords

Biomarkers
Empiric antibiotics
Goal-directed therapy
Septic shock
Severe sepsis
Vasoactive agents

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10.1016/j.idc.2009.04.002

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title = "The Management of Severe Sepsis and Septic Shock",

abstract = "The diagnosis and management of severe sepsis and septic shock is a complex and dynamic process. Newer evidence-based interventions are constantly being developed and implemented with the purpose of improving morbidity and mortality. Current investigations are being performed in hospital environments to determine the change in behaviors and clinical impact with the most recent recommendations. The use of standardized treatment protocols in addition to newer diagnostic and treatment modalities in patients who have severe sepsis and septic shock can continue to improve patient-related outcomes and the damaging effect of these diseases on society.",

keywords = "Biomarkers, Empiric antibiotics, Goal-directed therapy, Septic shock, Severe sepsis, Vasoactive agents",

author = "Morrell, {Matthew R.} and Micek, {Scott T.} and Kollef, {Marin H.}",

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N2 - The diagnosis and management of severe sepsis and septic shock is a complex and dynamic process. Newer evidence-based interventions are constantly being developed and implemented with the purpose of improving morbidity and mortality. Current investigations are being performed in hospital environments to determine the change in behaviors and clinical impact with the most recent recommendations. The use of standardized treatment protocols in addition to newer diagnostic and treatment modalities in patients who have severe sepsis and septic shock can continue to improve patient-related outcomes and the damaging effect of these diseases on society.

AB - The diagnosis and management of severe sepsis and septic shock is a complex and dynamic process. Newer evidence-based interventions are constantly being developed and implemented with the purpose of improving morbidity and mortality. Current investigations are being performed in hospital environments to determine the change in behaviors and clinical impact with the most recent recommendations. The use of standardized treatment protocols in addition to newer diagnostic and treatment modalities in patients who have severe sepsis and septic shock can continue to improve patient-related outcomes and the damaging effect of these diseases on society.

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KW - Empiric antibiotics

KW - Goal-directed therapy

KW - Septic shock

KW - Severe sepsis

KW - Vasoactive agents

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The Management of Severe Sepsis and Septic Shock

Abstract

Keywords

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