The mammalian target of rapamycin signaling pathway mediates epileptogenesis in a model of temporal lobe epilepsy

Keyphrases

• Temporal Lobe Epilepsy 100%
• Epileptogenesis 100%
• Mammalian Target of Rapamycin Signaling Pathway 100%
• Kainate 80%
• Epilepsy 80%
• Hippocampus 60%
• Mammalian Target of Rapamycin (mTOR) 60%
• MTOR Inhibitor 60%
• Status Epilepticus 60%
• Phospho-S6 60%
• Rat Model 40%
• Chronic Phase 40%
• Mammalian Target of Rapamycin Signaling 40%
• Neurogenesis 40%
• Mossy Fiber Sprouting 40%
• Tuberous Sclerosis Complex 20%
• Mouse Model 20%
• Molecular Mechanism 20%
• Seizure 20%
• Rapamycin 20%
• Effective Therapy 20%
• Neuronal Cell Death 20%
• Neuronal Death 20%
• Acute Phase 20%
• Neocortex 20%
• Seizure Activity 20%
• Mammalian Target of Rapamycin Pathway 20%
• Induced Neuronal Cells 20%
• Seizure Onset 20%
• Acute Symptomatic Seizures 20%
• Antiepileptogenic 20%
• Rapamycin Treatment 20%
• Kainate-induced Seizure 20%
• Initial Rise 20%
• Biphasic Activation 20%

Neuroscience

• Cell Signaling 100%
• Mammalian Target of Rapamycin 100%
• Temporal Lobe Epilepsy 100%
• Epileptogenesis 100%
• Hippocampus 27%
• Status Epilepticus 27%
• Neuronal Cell Death 18%
• Neurogenesis 18%
• Sirolimus 18%
• Tuberous Sclerosis 9%