The Liver as a Hub in Thermogenesis

Nada A. Abumrad

doi:10.1016/j.cmet.2017.08.018

The Liver as a Hub in Thermogenesis

Nada A. Abumrad

Research output: Contribution to journal › Short survey › peer-review

32 Scopus citations

Abstract

Manipulating thermogenesis could increase energy expenditure and improve metabolism. Brown fat is a major site of nonshivering thermogenesis, but other tissues, notably muscle and liver, can contribute to cold adaptation. In this issue, Simcox et al. (2017) demonstrate in cold-exposed mice that liver-generated acylcarnitines are required to fuel thermogenesis.

Original language	English
Pages (from-to)	454-455
Number of pages	2
Journal	Cell metabolism
Volume	26
Issue number	3
DOIs	https://doi.org/10.1016/j.cmet.2017.08.018
State	Published - Sep 5 2017

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10.1016/j.cmet.2017.08.018

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title = "The Liver as a Hub in Thermogenesis",

abstract = "Manipulating thermogenesis could increase energy expenditure and improve metabolism. Brown fat is a major site of nonshivering thermogenesis, but other tissues, notably muscle and liver, can contribute to cold adaptation. In this issue, Simcox et al. (2017) demonstrate in cold-exposed mice that liver-generated acylcarnitines are required to fuel thermogenesis.",

author = "Abumrad, {Nada A.}",

note = "Publisher Copyright: {\textcopyright} 2017 Elsevier Inc.",

year = "2017",

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doi = "10.1016/j.cmet.2017.08.018",

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T1 - The Liver as a Hub in Thermogenesis

AU - Abumrad, Nada A.

PY - 2017/9/5

Y1 - 2017/9/5

N2 - Manipulating thermogenesis could increase energy expenditure and improve metabolism. Brown fat is a major site of nonshivering thermogenesis, but other tissues, notably muscle and liver, can contribute to cold adaptation. In this issue, Simcox et al. (2017) demonstrate in cold-exposed mice that liver-generated acylcarnitines are required to fuel thermogenesis.

AB - Manipulating thermogenesis could increase energy expenditure and improve metabolism. Brown fat is a major site of nonshivering thermogenesis, but other tissues, notably muscle and liver, can contribute to cold adaptation. In this issue, Simcox et al. (2017) demonstrate in cold-exposed mice that liver-generated acylcarnitines are required to fuel thermogenesis.

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U2 - 10.1016/j.cmet.2017.08.018

DO - 10.1016/j.cmet.2017.08.018

M3 - Short survey

C2 - 28877451

AN - SCOPUS:85028678105

SN - 1550-4131

VL - 26

SP - 454

EP - 455

JO - Cell metabolism

JF - Cell metabolism

IS - 3

ER -

The Liver as a Hub in Thermogenesis

Abstract

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