The Landmark Series: Breast Conservation Trials (including oncoplastic breast surgery)

Julie A. Margenthaler, Jill R. Dietz, Abhishek Chatterjee

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


Significant progress has been made in the treatment and outcome of breast cancer. Some of the most dramatic strides have been in the surgical management of breast cancer. Breast-conserving therapy (BCT), including wide local excision of the tumor followed by irradiation, has become a standard treatment option for women with early-stage invasive breast cancer. Large cooperative group trials have contributed to the paradigm shift from mastectomy to BCT. This review reports the landmark BCT trials that provided the data for current surgical practices. The review also describes the body of literature contributing to the increasing use of oncoplastic techniques for patients undergoing BCT.

Original languageEnglish
Pages (from-to)2120-2127
Number of pages8
JournalAnnals of Surgical Oncology
Issue number4
StatePublished - Apr 2021


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