TY - JOUR
T1 - The Landmark Series
T2 - Breast Conservation Trials (including oncoplastic breast surgery)
AU - Margenthaler, Julie A.
AU - Dietz, Jill R.
AU - Chatterjee, Abhishek
N1 - Publisher Copyright:
© 2021, Society of Surgical Oncology.
PY - 2021/4
Y1 - 2021/4
N2 - Significant progress has been made in the treatment and outcome of breast cancer. Some of the most dramatic strides have been in the surgical management of breast cancer. Breast-conserving therapy (BCT), including wide local excision of the tumor followed by irradiation, has become a standard treatment option for women with early-stage invasive breast cancer. Large cooperative group trials have contributed to the paradigm shift from mastectomy to BCT. This review reports the landmark BCT trials that provided the data for current surgical practices. The review also describes the body of literature contributing to the increasing use of oncoplastic techniques for patients undergoing BCT.
AB - Significant progress has been made in the treatment and outcome of breast cancer. Some of the most dramatic strides have been in the surgical management of breast cancer. Breast-conserving therapy (BCT), including wide local excision of the tumor followed by irradiation, has become a standard treatment option for women with early-stage invasive breast cancer. Large cooperative group trials have contributed to the paradigm shift from mastectomy to BCT. This review reports the landmark BCT trials that provided the data for current surgical practices. The review also describes the body of literature contributing to the increasing use of oncoplastic techniques for patients undergoing BCT.
UR - http://www.scopus.com/inward/record.url?scp=85100012524&partnerID=8YFLogxK
U2 - 10.1245/s10434-020-09534-y
DO - 10.1245/s10434-020-09534-y
M3 - Article
C2 - 33521897
AN - SCOPUS:85100012524
SN - 1068-9265
VL - 28
SP - 2120
EP - 2127
JO - Annals of Surgical Oncology
JF - Annals of Surgical Oncology
IS - 4
ER -