TY - JOUR
T1 - The IPTA Nashville consensus conference on Post-Transplant lymphoproliferative disorders after solid organ transplantation in children
T2 - II—consensus guidelines for prevention
AU - Green, Michael
AU - Squires, James E.
AU - Chinnock, Richard E.
AU - Comoli, Patrizia
AU - Danziger-Isakov, Lara
AU - Dulek, Daniel E.
AU - Esquivel, Carlos O.
AU - Höcker, Britta
AU - L'Huillier, Arnaud G.
AU - Mazariegos, George Vincent
AU - Visner, Gary A.
AU - Bollard, Catherine M.
AU - Dipchand, Anne I.
AU - Ferry, Judith A.
AU - Gross, Thomas G.
AU - Hayashi, Robert
AU - Maecker-Kolhoff, Britta
AU - Marks, Stephen
AU - Martinez, Olivia M.
AU - Metes, Diana M.
AU - Michaels, Marian G.
AU - Preiksaitis, Jutta
AU - Smets, Françoise
AU - Swerdlow, Stephen H.
AU - Trappe, Ralf U.
AU - Wilkinson, James D.
AU - Allen, Upton
AU - Webber, Steven A.
AU - Dharnidharka, Vikas R.
N1 - Publisher Copyright:
© 2022 Wiley Periodicals LLC.
PY - 2024/2
Y1 - 2024/2
N2 - The International Pediatric Transplant Association (IPTA) convened an expert consensus conference to assess current evidence and develop recommendations for various aspects of care relating to post-transplant lymphoproliferative disorder after solid organ transplantation in children. In this report from the Prevention Working Group, we reviewed the existing literature regarding immunoprophylaxis and chemoprophylaxis, and pre-emptive strategies. While the group made a strong recommendation for pre-emptive reduction of immunosuppression at the time of EBV DNAemia (low to moderate evidence), no recommendations for use could be made for any prophylactic strategy or alternate pre-emptive strategy, largely due to insufficient or conflicting evidence. Current gaps and future research priorities are highlighted.
AB - The International Pediatric Transplant Association (IPTA) convened an expert consensus conference to assess current evidence and develop recommendations for various aspects of care relating to post-transplant lymphoproliferative disorder after solid organ transplantation in children. In this report from the Prevention Working Group, we reviewed the existing literature regarding immunoprophylaxis and chemoprophylaxis, and pre-emptive strategies. While the group made a strong recommendation for pre-emptive reduction of immunosuppression at the time of EBV DNAemia (low to moderate evidence), no recommendations for use could be made for any prophylactic strategy or alternate pre-emptive strategy, largely due to insufficient or conflicting evidence. Current gaps and future research priorities are highlighted.
UR - http://www.scopus.com/inward/record.url?scp=85142101299&partnerID=8YFLogxK
U2 - 10.1111/petr.14350
DO - 10.1111/petr.14350
M3 - Review article
C2 - 36369745
AN - SCOPUS:85142101299
SN - 1397-3142
VL - 28
JO - Pediatric transplantation
JF - Pediatric transplantation
IS - 1
M1 - e14350
ER -