The interferon-stimulated gene Ifi27l2a restricts West Nile virus infection and pathogenesis in a cell-typeand region-specific manner

Medicine & Life Sciences

• Antiviral Agents 29%
• Brain Stem 31%
• Cell Culture Techniques 13%
• Cell Death 13%
• Central Nervous System 12%
• Central Nervous System Infections 21%
• Cerebellum 32%
• Dendritic Cells 15%
• Ectopic Gene Expression 19%
• Fibroblasts 12%
• Flavivirus 22%
• Gene Silencing 18%
• Genes 28%
• Infections 8%
• Interferon-beta 20%
• Interferons 64%
• Macrophages 12%
• Neurons 32%
• Phenotype 10%
• Primary Cell Culture 21%
• Spinal Cord 14%
• Viral Load 16%
• Virus Diseases 25%
• West Nile Fever 100%
• West Nile virus 22%

Agriculture & Biology

• brain stem 22%
• cell culture 15%
• cell death 9%
• cells 22%
• central nervous system 19%
• cerebellum 22%
• dendritic cells 13%
• fibroblasts 8%
• Flavivirus 13%
• gene silencing 10%
• genes 24%
• granules 8%
• infection 36%
• interferon-beta 14%
• interferons 79%
• lethal genes 9%
• macrophages 8%
• mice 11%
• neurons 24%
• pathogenesis 63%
• pathogens 5%
• phenotype 6%
• pretreatment 7%
• spinal cord 10%
• tissues 4%
• viral load 11%
• virus replication 11%
• West Nile virus 88%