The insatiable quest for near-infrared fluorescent probes for molecular imaging

Samuel Achilefu

Research output: Contribution to journalArticlepeer-review

67 Scopus citations

Abstract

A multitalented protein: Fluorescence and bioluminescence resonance energy transfer, FRET and BRET, respectively, are viable strategies for the generation of near-infrared light for in vivo imaging. In a recent ground-breaking study, luciferase was used first to mediate the growth and stability of quantum dots and then as a light source for BRET (see picture).

Original languageEnglish
Pages (from-to)9816-9818
Number of pages3
JournalAngewandte Chemie - International Edition
Volume49
Issue number51
DOIs
StatePublished - Dec 17 2010

Keywords

  • bioluminescence
  • energy transfer
  • fluorescent proteins
  • near-infrared dyes
  • quantum dots

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