TY - JOUR
T1 - The influence of potassium and bicarbonate on red blood cell sodium in the doca-hypertensive pig
AU - Gierada, David S.
AU - Bohr, David F.
N1 - Funding Information:
The effects of plasma potassium, and blood bicarbonate on red blood cell sodium were studied & + in seven pigs implanted subcutaneously with DOCA (100 mg/kg) impregnated i n Silastic. Mean arterial pressure, red blood cell sodium, plasma sodium, plasma potassium, and blood bicarbonate were measured from 5 days pre-implant to 30 days post-implant. One day post-implant, the pigs had significant increases in mean arterial pressure and red cell sodium content, and a significant decrease in plasma potassium concentration. In KC1 infusion studies when plasma potassium was raised an average of Send all correspondence to: Dr. David F. Bohr Department of Physiology 7710 Medical Science Bldg I1 University of Michigan Ann Arbor, M I 48109 This work was supported by a grant (HL 18575) from the National Institutes of Health.
PY - 1988
Y1 - 1988
N2 - The effects of plasma potassium, and blood bicarbonate on red blood cell sodium were studied in vivo in seven pigs implanted subcutaneously with DOCA (100 mg/kg) impregnated in Silastic. Mean arterial pressure, red blood cell sodium, plasma sodium, plasma potassium, and blood bicarbonate were measured from 5 days pre-implant to 30 days post-implant. One day post-implant, the pigs had significant increases in mean arterial pressure and red cell sodium content, and a significant decrease in plasma potassium concentration. In KC1 infusion studies when plasma potassium was raised an average of
AB - The effects of plasma potassium, and blood bicarbonate on red blood cell sodium were studied in vivo in seven pigs implanted subcutaneously with DOCA (100 mg/kg) impregnated in Silastic. Mean arterial pressure, red blood cell sodium, plasma sodium, plasma potassium, and blood bicarbonate were measured from 5 days pre-implant to 30 days post-implant. One day post-implant, the pigs had significant increases in mean arterial pressure and red cell sodium content, and a significant decrease in plasma potassium concentration. In KC1 infusion studies when plasma potassium was raised an average of
KW - Anion channels
KW - Hypertensive mechanism
KW - Hypokalemia
KW - Sodium pump
UR - http://www.scopus.com/inward/record.url?scp=0023891364&partnerID=8YFLogxK
U2 - 10.3109/10641968809103526
DO - 10.3109/10641968809103526
M3 - Article
C2 - 3370847
AN - SCOPUS:0023891364
SN - 1064-1963
VL - A10
SP - 249
EP - 271
JO - Clinical and Experimental Hypertension
JF - Clinical and Experimental Hypertension
IS - 2
ER -