TY - JOUR
T1 - The inception of cavitation bubble clouds induced by high-intensity focused ultrasound
AU - Chen, Hong
AU - Li, Xiaojing
AU - Wan, Mingxi
N1 - Funding Information:
The work was supported by the National Natural Science Foundation of China (No. 30370403) and the China Specialized Research Fund for the Doctoral Program of Higher Education (No.20030698016).
PY - 2006/12/22
Y1 - 2006/12/22
N2 - In many therapeutic applications of high-intensity focused ultrasound (HIFU) the appearance of cavitation bubbles is unavoidable, whereas the dynamics of the bubbles induced by HIFU have not been clarified. The objective of the present work is to observe the inception process of cavitation bubble clouds generated by HIFU transducer in water using high-speed photography. Sequential images captured within 600 μs after the onset of ultrasound transmission show the dynamics of cavitation bubbles' generation, growth, deformation, expansion and collapse in the focal region. However, when the observation time is narrowed to the initial 145 μs, both the still and streak images reveal that the cavitation bubbles astonishingly stay stable in the focal region for at least 60 μs. The results imply that through adjusting the HIFU exposure time while other physical parameters are appropriately chosen, it might be possible to control the generation of stable cavitation bubbles locally in the focal region.
AB - In many therapeutic applications of high-intensity focused ultrasound (HIFU) the appearance of cavitation bubbles is unavoidable, whereas the dynamics of the bubbles induced by HIFU have not been clarified. The objective of the present work is to observe the inception process of cavitation bubble clouds generated by HIFU transducer in water using high-speed photography. Sequential images captured within 600 μs after the onset of ultrasound transmission show the dynamics of cavitation bubbles' generation, growth, deformation, expansion and collapse in the focal region. However, when the observation time is narrowed to the initial 145 μs, both the still and streak images reveal that the cavitation bubbles astonishingly stay stable in the focal region for at least 60 μs. The results imply that through adjusting the HIFU exposure time while other physical parameters are appropriately chosen, it might be possible to control the generation of stable cavitation bubbles locally in the focal region.
KW - Bubbles
KW - Cavitation
KW - Control
KW - High-intensity focused ultrasound
KW - High-speed photography
UR - http://www.scopus.com/inward/record.url?scp=33845879908&partnerID=8YFLogxK
U2 - 10.1016/j.ultras.2006.05.021
DO - 10.1016/j.ultras.2006.05.021
M3 - Article
C2 - 16782158
AN - SCOPUS:33845879908
SN - 0041-624X
VL - 44
SP - e427-e429
JO - Ultrasonics
JF - Ultrasonics
IS - SUPPL.
ER -