TY - JOUR
T1 - The Impact of Gastroparesis on Medical Therapy for Gastroesophageal Reflux Disease
AU - Reddy, Alexander
AU - Gyawali, C. Prakash
AU - Patel, Amit
N1 - Publisher Copyright:
© The Author(s) 2023.
PY - 2024/9
Y1 - 2024/9
N2 - Symptoms suspicious for gastroesophageal reflux disease (GERD) represent frequent indications for medical presentation, as do symptoms potentially compatible with delayed gastric emptying. In this clinical setting, care must be taken to characterize patient symptoms accurately, and also appropriately evaluate for pathophysiologic processes including visceral hypersensitivity, rumination syndrome, supragastric belching, cannabinoid hyperemesis, and cyclic vomiting syndrome. While proton pump inhibitors (PPI) are the foundation of medical management of GERD, delayed gastric emptying is a downstream factor that can promote gastroesophageal reflux and warrants tailored clinical management. Specifically, patients with refractory symptoms in the setting of GERD and delayed gastric emptying may benefit from personalized adjunct medical therapy with prokinetics.
AB - Symptoms suspicious for gastroesophageal reflux disease (GERD) represent frequent indications for medical presentation, as do symptoms potentially compatible with delayed gastric emptying. In this clinical setting, care must be taken to characterize patient symptoms accurately, and also appropriately evaluate for pathophysiologic processes including visceral hypersensitivity, rumination syndrome, supragastric belching, cannabinoid hyperemesis, and cyclic vomiting syndrome. While proton pump inhibitors (PPI) are the foundation of medical management of GERD, delayed gastric emptying is a downstream factor that can promote gastroesophageal reflux and warrants tailored clinical management. Specifically, patients with refractory symptoms in the setting of GERD and delayed gastric emptying may benefit from personalized adjunct medical therapy with prokinetics.
KW - ambulatory reflux monitoring
KW - erosive esophagitis
KW - gastric emptying
KW - prokinetics
KW - reflux
UR - http://www.scopus.com/inward/record.url?scp=85205304659&partnerID=8YFLogxK
U2 - 10.1177/26345161231211758
DO - 10.1177/26345161231211758
M3 - Article
AN - SCOPUS:85205304659
SN - 2634-5161
VL - 4
SP - 255
EP - 263
JO - Foregut
JF - Foregut
IS - 3
ER -