109 Scopus citations


This review explores the principle features of the immunopathology of multiple sclerosis (MS), particularly relapsing-remitting MS. It highlights the emerging concepts in the pathogenesis of MS in the context of known features of pathology, including the characterization of cytokine networks promoting inflammatory damage of the central nervous system, B-cell involvement, and inflammatory damage of axons and neurons. This article preferentially focuses on MS rather than animal models of the disease, such as experimental autoimmune encephalomyelitis.

Original languageEnglish
Pages (from-to)257-278
Number of pages22
JournalNeurologic Clinics
Issue number2
StatePublished - May 2011


  • Demyelination
  • Multiple sclerosis
  • Neuroimmunology
  • Pathogenesis


Dive into the research topics of 'The Immunopathophysiology of Multiple Sclerosis'. Together they form a unique fingerprint.

Cite this