TY - JOUR
T1 - The ICT filariasis test
T2 - A rapid-format antigen test for diagnosis of bancroftian filariasis
AU - Weil, G. J.
AU - Lammie, P. J.
AU - Weiss, N.
N1 - Funding Information:
Ac k~,owledgements Bames-jewish Hospital has licensed ma'erials to ICT D~agnnstics for use in th~ ICf Filariasis test I~t. ICT D agnost cs pr~,vided free i,,i~ tc a~\[t hre.e !abo,~,.~tone~~ r ~valuation withc, ut i~ayrrient ,~or"t esbng and without restrictiGns or, the oat~ o0tained. Well's laboratory =s supported in part by the National Institutes ef Health and WHO/\[DR. Fanya Li~.is provi:ted excellent technical sLippo*'L Lammie's work in Haiti was supported in part by grants from WHO/l-DR and USAID. N~-k Ebe4"a~ and David Addiss participated in studies in Haitl that generate~i serum samples tested in this study. The Filanasis Serum ~.,ankw as s'Jppor'ted in part by TDFU~A/t=iG. A~nelise Oett!, provided e;<celle:lt :ethnical support in Basle.
PY - 1997
Y1 - 1997
N2 - Antigen testing is now recognized as the method of choice for detection of Wuchereria bancrofti infections. Unlike tests that detect microfilariae, antigen tests can be performed with blood collected during the day or night. However, existing enzyme-linked immunosorbent assay (ELISA) tests for filarial antigenemia are difficult to perform in the field, and this has limited their use in endemic countries. In this article, Gary Weil, Patrick Lammie and Niggi Weiss review their experience with a new rapid-format filarial antigen test. They found that the ICT card test was very easy to perform and that it was comparable with ELISA for the detection of filarial antigen in sera from people with microfilaremia. The introduction now of an antigen test suitable for use in the field is especially timely, in that it may facilitate implementation of new strategies proposed by the World Health Organization for control and elimination of lymphatic filariasis.
AB - Antigen testing is now recognized as the method of choice for detection of Wuchereria bancrofti infections. Unlike tests that detect microfilariae, antigen tests can be performed with blood collected during the day or night. However, existing enzyme-linked immunosorbent assay (ELISA) tests for filarial antigenemia are difficult to perform in the field, and this has limited their use in endemic countries. In this article, Gary Weil, Patrick Lammie and Niggi Weiss review their experience with a new rapid-format filarial antigen test. They found that the ICT card test was very easy to perform and that it was comparable with ELISA for the detection of filarial antigen in sera from people with microfilaremia. The introduction now of an antigen test suitable for use in the field is especially timely, in that it may facilitate implementation of new strategies proposed by the World Health Organization for control and elimination of lymphatic filariasis.
UR - http://www.scopus.com/inward/record.url?scp=0030873801&partnerID=8YFLogxK
U2 - 10.1016/S0169-4758(97)01130-7
DO - 10.1016/S0169-4758(97)01130-7
M3 - Article
C2 - 15275155
AN - SCOPUS:0030873801
SN - 0169-4758
VL - 13
SP - 401
EP - 404
JO - Parasitology Today
JF - Parasitology Today
IS - 10
ER -