The Hybrid Transoral-Pharyngotomy Approach to Oropharyngeal Carcinoma: Technique and Outcome

Parul Sinha, Patrik Pipkorn, Joseph Zenga, Bruce H. Haughey

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Background: The indications, techniques, and outcomes for a minimally invasive surgical approach in oropharyngeal squamous cell carcinoma (OPSCC) unsuitable for transoral resection are not well-described. Methods: A retrospective case series was performed using a prospectively assembled database of transoral surgery-treated OPSCC patients who also underwent a "hybrid" approach of combined transoral and limited pharyngotomy for tumor resection. Disease and functional outcomes were evaluated. Results: Twenty patients underwent complete tumor resection using the hybrid approach. Median follow-up was 48 months. No postoperative pharyngocutaneous fistula occurred. One patient (5%) had a local recurrence. Kaplan-Meier estimates for disease-specific survival at 2 and 5 years were 94.4% (95% CI, 84%-100%) and 87% (95% CI, 70%-100%). All but 1 patient (due to chemoradiotherapy-related chondroradionecrosis) were decannulated, and 2 required long-term gastrostomy. Conclusion: In the absence of a favorable transoral access, the "hybrid" approach of combined transoral and limited pharyngotomy can accomplish margin-negative primary tumor resection, with a high degree of disease control and functional recovery in selected OPSCC patients.

Original languageEnglish
Pages (from-to)357-364
Number of pages8
JournalAnnals of Otology, Rhinology and Laryngology
Volume126
Issue number5
DOIs
StatePublished - May 1 2017

Keywords

  • minimally invasive surgical technology
  • oropharynx cancer
  • p16 positive
  • pharyngotomy
  • transoral laser microsurgery

Fingerprint

Dive into the research topics of 'The Hybrid Transoral-Pharyngotomy Approach to Oropharyngeal Carcinoma: Technique and Outcome'. Together they form a unique fingerprint.

Cite this