The human pancreatic lipase-encoding gene: structure and conservation of an Alu sequence in the lipase gene family

Harold F. Sims, Martha L. Jennens, Mark E. Lowe

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

The isolation and characterization of the human gene (hPL) encoding pancreatic lipase is reported. The gene has 13 exons dispersed in about 20 kb of genomic DNA. A pseudogene of hPL was also partially characterized. An Alu sequence is conserved in the homologous introns of hPL and the lipoprotein lipase-encoding gene.

Original languageEnglish
Pages (from-to)281-285
Number of pages5
JournalGene
Volume131
Issue number2
DOIs
StatePublished - Sep 15 1993

Keywords

  • Recombinant DNA
  • canine
  • flanking sequences
  • introns
  • nucleotide sequencing
  • phylogeny
  • pseudogene
  • triglycerides

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