Abstract
The human heat-inducible Hsp70B and Hsp70B' genes were co-localized to 1q23.1 by in situ hybridization. However, though transcripts from Hsp70B could be detected in heat-shocked cells, DNA sequence analyses of both the gene and cDNA copies of the mRNA indicate the gene is non-functional. Moreover, mouse homologues of Hsp70B/B' were not detected by Southern blot analysis, suggesting Hsp70B/B' arose from either Hsp70-1or Hsp70-2 after the divergence of mice and humans.
Original language | English |
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Pages (from-to) | 201-205 |
Number of pages | 5 |
Journal | BBA - Biochimica et Biophysica Acta |
Volume | 1494 |
Issue number | 1-2 |
DOIs | |
State | Published - Nov 15 2000 |