The great recession and immune function

  • Elizabeth McClure
  • , Lydia Feinstein
  • , Sara Ferrando-Martínez
  • , Manuel Leal
  • , Sandro Galea
  • , Allison E. Aiello

Research output: Contribution to journalArticlepeer-review

Abstract

The Great Recession precipitated unprecedented home foreclosures increases, but documentation of related neighborhood changes and population health is scant. Using the Detroit Neighborhood Health Study (N = 277), we examined associations between neighborhood-level recession indicators and thymic function, a life course immunological health indicator. In covariate-adjusted multilevel models, each 10 percentage point increase in abandoned home prevalence and 1 percentage point increase in 2009 home foreclosures was associated with 1.7-year and 3.3-year increases in thymic aging, respectively. Associations attenuated after adjustment for neighborhood-level social cohesion, suggesting community ties may buffer recession-related immune aging. Effects of neighborhood stressors were strongest in middle-income households, supporting theory of excess vulnerability in this group. Future research should assess whether ongoing foreclosure and blight reduction efforts improve health for residents of recession impacted neighborhoods.

Original languageEnglish
Pages (from-to)62-81
Number of pages20
JournalRSF
Volume4
Issue number4
DOIs
StatePublished - Apr 2018

Keywords

  • Detroit
  • Immunity
  • Immunosenescence
  • Neighborhood
  • Social determinants of health
  • Thymic function

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