The genetics of vitamin K antagonists

Research output: Contribution to journalComment/debate

12 Scopus citations

Abstract

In summary, the results of rigorous and creative experiments performed by these investigators confirm the discovery of a novel reductase with VKOR activity. In vivo, VKOR likely functions in conjunction with other proteins to form a complex in the endoplasmic reticulum. Knowledge of the new gene should help in understanding the mechanism of γ-carboxylation of clotting factors and other proteins and may aid in the development of novel drugs.

Original languageEnglish
Pages (from-to)224-225
Number of pages2
JournalPharmacogenomics Journal
Volume4
Issue number4
DOIs
StatePublished - Sep 7 2004

Fingerprint Dive into the research topics of 'The genetics of vitamin K antagonists'. Together they form a unique fingerprint.

Cite this