The genetic of other polyposis syndromes

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


In addition to familial adenomatous polyposis, several other rare, but well-described, inherited polyposis syndromes may be encountered in the practice of colon and rectal surgery. Many of these syndromes predispose to both gastrointestinal and extraintestinal malignancies. Knowledge of these syndromes and their manifestations is important in recognizing patients and kindreds with these diseases. In many cases, the identification of the genes involved in these syndromes allows for the genetic screening of both index cases and kindreds of patients with intestinal polyposis. As our knowledge of the genetics involved in these polyposis syndromes expands, our understanding of the pathogenesis of gastrointestinal malignancies is enhanced.

Original languageEnglish
Pages (from-to)158-162
Number of pages5
JournalSeminars in Colon and Rectal Surgery
Issue number3
StatePublished - Sep 2004


  • BMPR1A
  • Juvenile polyps
  • PTEN
  • Peutz-Jeghers syndrome
  • SMAD4
  • STK11


Dive into the research topics of 'The genetic of other polyposis syndromes'. Together they form a unique fingerprint.

Cite this