The future of the human connectome

D. C. Van Essen, K. Ugurbil

Research output: Contribution to journalReview article

129 Scopus citations

Abstract

The opportunity to explore the human connectome using cutting-edge neuroimaging methods has elicited widespread interest. How far will the field be able to progress in deciphering long-distance connectivity patterns and in relating differences in connectivity to phenotypic characteristics in health and disease? We discuss the daunting nature of this challenge in relation to specific complexities of brain circuitry and known limitations of in vivo imaging methods. We also discuss the excellent prospects for continuing improvements in data acquisition and analysis. Accordingly, we are optimistic that major insights will emerge from human connectomics in the coming decade.

Original languageEnglish
Pages (from-to)1299-1310
Number of pages12
JournalNeuroImage
Volume62
Issue number2
DOIs
StatePublished - Aug 15 2012

Keywords

  • 7 Tesla
  • Brain
  • Connectivity
  • Diffusion imaging
  • FMRI
  • Functional imaging
  • MRI
  • Magnetic Resonance Imaging
  • Multiband
  • Resting state
  • Tractography
  • Ultrahigh field imaging

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