TY - JOUR
T1 - The functional sequelae of sacrococcygeal teratoma
T2 - a longitudinal and cross-sectional follow-up study
AU - Cozzi, Francesco
AU - Schiavetti, Amalia
AU - Zani, Augusto
AU - Spagnol, Lorna
AU - Totonelli, Giorgia
AU - Cozzi, Denis A.
PY - 2008/4
Y1 - 2008/4
N2 - Aim: The purpose of the study was to determine clinical manifestations, prevalence, and natural history of functional sequelae in patients operated on for sacrococcygeal teratoma (SCT) during infancy. Methods: The medical records of 18 infants operated on for SCT were reviewed. Data recorded during admission and during routine outpatient appointments were analyzed. Moreover, 13 surviving patients (mean age, 25 years) and 65 age- and sex-matched controls were evaluated at a special outpatient clinic. Results: Seven adult patients and 25 controls presented with one or more functional disorders including abdominal pain, constipation, diarrhea, soiling, enuresis, urinary frequency, urinary stress incontinence, and urinary straining. In 7 of 8 symptomatic children, one or more functional disorders disappeared during adult life. In comparison with controls, adult patients had a nonsignificant higher prevalence of each individual dysfunction. Conclusions: Sequelae of SCT tend to improve with time, and the disorders reported are relatively common complaints in the general population.
AB - Aim: The purpose of the study was to determine clinical manifestations, prevalence, and natural history of functional sequelae in patients operated on for sacrococcygeal teratoma (SCT) during infancy. Methods: The medical records of 18 infants operated on for SCT were reviewed. Data recorded during admission and during routine outpatient appointments were analyzed. Moreover, 13 surviving patients (mean age, 25 years) and 65 age- and sex-matched controls were evaluated at a special outpatient clinic. Results: Seven adult patients and 25 controls presented with one or more functional disorders including abdominal pain, constipation, diarrhea, soiling, enuresis, urinary frequency, urinary stress incontinence, and urinary straining. In 7 of 8 symptomatic children, one or more functional disorders disappeared during adult life. In comparison with controls, adult patients had a nonsignificant higher prevalence of each individual dysfunction. Conclusions: Sequelae of SCT tend to improve with time, and the disorders reported are relatively common complaints in the general population.
KW - Abdominal pain
KW - Colitis
KW - Tumor
UR - https://www.scopus.com/pages/publications/41549125832
U2 - 10.1016/j.jpedsurg.2007.10.066
DO - 10.1016/j.jpedsurg.2007.10.066
M3 - Article
C2 - 18405712
AN - SCOPUS:41549125832
SN - 0022-3468
VL - 43
SP - 658
EP - 661
JO - Journal of Pediatric Surgery
JF - Journal of Pediatric Surgery
IS - 4
ER -