Abstract

Systemic glucose homeostasis is primarily regulated by insulin, which targets liver, fat, and skeletal muscle cells, setting up important feedback loops. New studies now show that the osteoblast also has a significant role in modulating systemic insulin responses, via the insulin-regulated transcription factor FOXO1 and the hormone osteocalcin.

Original languageEnglish
Pages (from-to)175-176
Number of pages2
JournalCell metabolism
Volume11
Issue number3
DOIs
StatePublished - Mar 3 2010

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