Systemic glucose homeostasis is primarily regulated by insulin, which targets liver, fat, and skeletal muscle cells, setting up important feedback loops. New studies now show that the osteoblast also has a significant role in modulating systemic insulin responses, via the insulin-regulated transcription factor FOXO1 and the hormone osteocalcin.

Original languageEnglish
Pages (from-to)175-176
Number of pages2
JournalCell metabolism
Issue number3
StatePublished - Mar 3 2010


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