The enantiomer of cholesterol

E. J. Westover; D. F. Covey

doi:10.1007/s00232-004-0714-7

The enantiomer of cholesterol

E. J. Westover
, D. F. Covey

Research output: Contribution to journal › Review article › peer-review

68 Scopus citations

Abstract

Cholesterol plays a variety of significant roles in biological systems. However, the mechanisms by which cholesterol functions remain largely unclear. The enantiomer of cholesterol (ent-cholesterol) - which has identical physical properties, but opposite three-dimensional configuration compared to cholesterol - is a unique tool that can be used to better understand the mechanisms of cholesterol function. We review the literature pertaining to ent-cholesterol, focusing in particular on its use in biological studies.

Original language	English
Pages (from-to)	61-72
Number of pages	12
Journal	Journal of Membrane Biology
Volume	202
Issue number	2
DOIs	https://doi.org/10.1007/s00232-004-0714-7
State	Published - Dec 2004

Keywords

Cholesterol
Enantiomer
Enantioselectivity
ent-Cholesterol

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10.1007/s00232-004-0714-7

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abstract = "Cholesterol plays a variety of significant roles in biological systems. However, the mechanisms by which cholesterol functions remain largely unclear. The enantiomer of cholesterol (ent-cholesterol) - which has identical physical properties, but opposite three-dimensional configuration compared to cholesterol - is a unique tool that can be used to better understand the mechanisms of cholesterol function. We review the literature pertaining to ent-cholesterol, focusing in particular on its use in biological studies.",

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AB - Cholesterol plays a variety of significant roles in biological systems. However, the mechanisms by which cholesterol functions remain largely unclear. The enantiomer of cholesterol (ent-cholesterol) - which has identical physical properties, but opposite three-dimensional configuration compared to cholesterol - is a unique tool that can be used to better understand the mechanisms of cholesterol function. We review the literature pertaining to ent-cholesterol, focusing in particular on its use in biological studies.

KW - Cholesterol

KW - Enantiomer

KW - Enantioselectivity

KW - ent-Cholesterol

UR - https://www.scopus.com/pages/publications/14644395532

U2 - 10.1007/s00232-004-0714-7

DO - 10.1007/s00232-004-0714-7

M3 - Review article

C2 - 15702370

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SP - 61

EP - 72

JO - Journal of Membrane Biology

JF - Journal of Membrane Biology

IS - 2

ER -

The enantiomer of cholesterol

Abstract

Keywords

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