The enantiomer of cholesterol

E. J. Westover, D. F. Covey

Research output: Contribution to journalReview articlepeer-review

64 Scopus citations


Cholesterol plays a variety of significant roles in biological systems. However, the mechanisms by which cholesterol functions remain largely unclear. The enantiomer of cholesterol (ent-cholesterol) - which has identical physical properties, but opposite three-dimensional configuration compared to cholesterol - is a unique tool that can be used to better understand the mechanisms of cholesterol function. We review the literature pertaining to ent-cholesterol, focusing in particular on its use in biological studies.

Original languageEnglish
Pages (from-to)61-72
Number of pages12
JournalJournal of Membrane Biology
Issue number2
StatePublished - Dec 2004


  • Cholesterol
  • Enantiomer
  • Enantioselectivity
  • ent-Cholesterol


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